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PepIQPeptide Research Library
What research actually shows — not marketing copy, not anecdote. Each page covers mechanism of action, what the data supports, what remains unknown, and common use cases. All framed as educational summaries, not medical advice.
Recovery & Repair
7 peptidesBPC-157
Broad tissue repair, gut healing, and tendon regeneration. The most studied recovery peptide.
TB-500
Thymosin Beta-4 fragment. Systemic healing via actin upregulation and angiogenesis.
GHK-Cu
Copper-binding tripeptide. Collagen synthesis, wound repair, and anti-aging skin research.
Thymosin Alpha-1
Thymus-derived immune modulator with antiviral and anti-tumor research. Approved in some countries.
AOD-9604
HGH fragment (176–191) studied for fat metabolism without IGF-1 or glucose effects.
LL-37
Human cathelicidin antimicrobial peptide. Innate immunity, wound healing, and anti-biofilm research.
KPV
Alpha-MSH-derived tripeptide. Potent anti-inflammatory effects studied in gut disease, wound healing, and skin conditions.
Growth Hormone
7 peptidesIpamorelin
Selective GHRP. Clean GH pulse with no meaningful cortisol or prolactin elevation.
CJC-1295
GHRH analogue. Amplifies GH pulse duration. Almost always paired with Ipamorelin.
Sermorelin
First 29 amino acids of endogenous GHRH. More physiological than synthetic GHRPs.
Tesamorelin
FDA-approved GHRH analogue (Egrifta). Clinical data on visceral fat reduction.
GHRP-2
Second-generation GHRP. Potent GH release with some cortisol and prolactin elevation.
GHRP-6
First widely studied GHRP. Strong GH pulse; notable hunger side effect via ghrelin.
Hexarelin
Most potent GHRP. Significant GH release with cardiac protective effects independent of GH.
GLP-1 / Metabolic
4 peptidesSemaglutide
FDA-approved GLP-1 agonist (Ozempic/Wegovy). ~15–17% average weight loss in trials.
Tirzepatide
Dual GIP/GLP-1 agonist (Mounjaro/Zepbound). Up to 21% weight loss in SURMOUNT trials.
Liraglutide
Daily GLP-1 agonist (Victoza/Saxenda). Longest safety track record in the GLP-1 class.
Retatrutide
Triple GLP-1/GIP/glucagon agonist in trials. Up to 24% weight loss in Phase 2 data.
Muscle & Growth
3 peptidesLongevity & Mitochondrial
5 peptidesEpithalon
Pineal tetrapeptide. Telomerase activation and telomere extension research.
Humanin
Mitochondria-derived peptide. Neuroprotection, anti-apoptosis, and age-related disease research.
MOTS-c
Mitochondrial peptide with exercise-mimetic and insulin-sensitizing properties.
SS-31
Mitochondria-targeting peptide (Elamipretide). Heart failure and oxidative stress research.
SLU-PP-332
ERRα agonist and exercise mimetic. Activates mitochondrial biogenesis pathways that mimic endurance training.
Nootropic & Neural
5 peptidesSemax
ACTH-derived nootropic. Rapid BDNF and NGF upregulation. Neuroprotection in Russian trials.
Selank
Anxiolytic without sedation or dependence. Tuftsin analogue with cognitive enhancement data.
Dihexa
HGF potentiator. Potentially the most potent cognitive-enhancing peptide identified to date.
VIP
Vasoactive Intestinal Peptide. Anti-inflammatory, immune modulating, and CIRS protocol research.
Pinealon
Pineal tripeptide. Neuroprotection and circadian rhythm regulation from Khavinson research group.
Libido & Melanocortin
4 peptidesPT-141
FDA-approved bremelanotide (Vyleesi). Central nervous system mechanism for sexual dysfunction.
Melanotan II
Non-selective melanocortin agonist. Tanning, libido, appetite suppression — broad side effect profile.
Melanotan I
Selective MC1R agonist (Afamelanotide/Scenesse). FDA-approved tanning without libido effects.
Kisspeptin
GnRH regulator. Hormone axis support, LH/FSH modulation, and fertility research.
Sleep & Immune
2 peptidesThe same audience researching peptides is asking about these compounds. Same evidence-first approach — what research shows, what remains unknown, and what the practical considerations are.
NAD+ / NMN / NR
NAD+ declines ~50% by age 60. NMN and NR are the two leading oral precursors — the debate over which is more effective is one of the most active in longevity research.
Glutathione
The body's master antioxidant. Oral bioavailability is limited — the IV vs liposomal vs precursor (NAC) debate is central to practical use.
Methylene Blue
Synthetic electron carrier that supports mitochondrial function. FDA-approved for one indication; increasingly studied for cognition and aging.
Berberine
Plant alkaloid that activates AMPK — the same pathway as metformin. Multiple RCTs showing glucose-lowering comparable to pharmaceutical options.
Rapamycin
mTOR inhibitor and the most consistently replicated longevity intervention in animal models. Off-label use in healthy aging adults is growing rapidly.
Metformin
The most prescribed diabetes drug in the world — now being studied as the first drug designed to target aging itself (TAME trial).
5-Amino-1MQ
NNMT inhibitor that raises NAD+ levels and activates fat metabolism. Research shows fat cell shrinkage and weight loss in obese animal models.
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