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Nootropic

Selank

Selank (TP-7)

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A synthetic heptapeptide developed in Russia with anxiolytic and nootropic properties studied in clinical trials. Approved in Russia for generalized anxiety.

Selank is not approved by the FDA for human use. It is sold strictly for research purposes only and is not intended for human consumption, diagnosis, treatment, or prevention of any disease or condition. Purchase and use is entirely at your own risk.

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What it is

Selank is a synthetic analogue of the naturally occurring tetrapeptide tuftsin (Thr-Lys-Pro-Arg). It was developed at the Institute of Molecular Genetics of the Russian Academy of Sciences and has undergone clinical trials in Russia with regulatory approval there for generalized anxiety disorder.

It has a unique pharmacological profile — anxiolytic without the sedation or dependence associated with benzodiazepines.

What research shows

  • Anxiolytic effects comparable to benzodiazepines without sedation or dependence in Russian trials
  • Improved cognitive function, memory, and attention in some studies
  • Upregulation of BDNF
  • Immune modulatory effects — affects IL-6 and interferon expression

What remains unknown

  • Reproducibility in Western clinical trial frameworks
  • Long-term safety profile
  • Exact mechanism underlying nootropic effects

Administration basics

Common use cases

Anxiety, cognitive enhancement, stress management.

Half-life

~1–2 minutes in blood (but CNS effects last much longer).

Administration

Intranasal drops or subcutaneous injection. Intranasal is most common.

Source this compound

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Research Protocols & Common Usage

Doses used in research

  • Russian clinical trials have used 250–500mcg intranasally per day
  • Community protocols commonly report similar doses of 250–500mcg/day

Administration routes studied

Intranasal (most studied and most common route)Subcutaneous injection

Typical protocol duration

Russian research protocols commonly ran 2–4 weeks. Community use includes both short cycles and longer maintenance protocols.

Common stacking protocols

  • Selank + Semax — the most commonly reported nootropic/anxiolytic combination
  • Selank + BPC-157 — combined in some anxiety-reduction protocols

Contraindications & combinations to avoid

  • Benzodiazepines and other anxiolytics — additive effects on anxiety pathways are possible
  • Psychiatric medications — caution when combining with medications acting on GABA or serotonin pathways

Dosing information reflects doses used in published research and commonly reported community protocols only. This is not a personal recommendation. These compounds are not FDA-approved for human use in the contexts described. Consult a qualified healthcare provider before starting any protocol.

Considering stacking?

See the stacking guide for common combinations with Selank and what to avoid.

Stacking guide

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Community Reviews

Reviews reflect individual user experiences with research compounds and are not medical advice. Results vary. These compounds are not FDA approved for human use. Peptelligent does not verify reported experiences.

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